Flow chemistry

EcoSynth is a solution provider for the chemical challenges of tomorrow. As an extra tool, flow chemistry (lab equivalent of continuous processing) has several advantages over the traditional batch chemistry:

 

Efficient
Flexible
 
Safe
Higher yield and purity  Different chemistries/reactors
on one instrument
Excellent heat transfer 

In-situ analytical
evaluation of reactions

Less restrictions
on minimum fill volumes 
Low reactor volume and hold up time 

Better process control

 Scaling out by adding units
in parallel
In-situ generation and consumption
of dangerous compounds 

Shorter time to commercial launch

   

 

 

In order to meet a wide range of synthesis requests (using traditional as well as unconventional activation techniques), Ecosynth is equipped with several flow instruments from different vendors.

Flow chemistry

  • Photochemical flow reactor (EcoSynth) Open or Close

    The instrument allows to run photochemical reactions and which have the following benefits:
    Photoflow at EcoSynth

    • Access to "thermal forbidden chemistries" and "unexplored chemical space"
    • Greener chemistry by shorter synthetic route

     

     

     

     

     

  • Asia Flux for Electrochemistry (Syrris) Open or Close

    The instrument allows to run electrochemical reactions which are characterized by:
    Asia Flux at EcoSynth

    • Reduction of reagent use: electrons are the most green reagents
    • Tunable reactions: either by selection of voltage or mode (constant current or constant voltage)

     

     

     

     

  • H-Cube Pro (ThalesNano) Open or Close

    The instrument allows a safe running of hydrogenation reactions in the following process window:H-Cube Pro at EcoSynth

    • Flow rate range: 0.3 - 3 mL/min
    • Temperature range: 10 - 150 °C
    • Pressure range: Atmospheric to 100 bar
    • Hydrogenation Production range: 0 – 60 cm3/min

     

     

     

     

  • R Series Vapourtec (Vapourtec) Open or Close

    The available reactors have the following characteristics and process window:
    Flow Chemistry at EcoSynth

    • Reactor volume: 2, 5, 10 ml
    • Reactor type: coiled, column, tube in tube (gas-liquid), UV-VIS transparant
    • Resistance: PFA, 316 stainless steel or Hastelloy®
    • Temperature: -70°C up to 250°C
    • Pressure: up to 40 bar

     

     

     

     

     

 

With this instrument park and knowing the advantages (and disadvantages) of both batch and flow chemistry combined with a sound chemical background of experienced chemists, we can provide optimized solutions for:

  • Homogeneous catalyzed reactions
  • Heterogeneous catalyzed reactions
  • Gas-liquid reactions
  • Liquid-liquid reactions
  • Reactions using alternative energy sources

 

 

Read our flow chemistry application note: Oxidation Using a Gas-Liquid Membrane Reactor